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Oxygenation is defined as how oxygen enters the lungs and reaches the body's tissues and is measured using SpO2 or ABGs.

Perfusion

Oxygenation

Oxygenation refers to how well oxygen moves from the lungs into the bloodstream and is delivered to tissues. Clinically, we assess oxygenation with SpO2 and arterial blood gases because pulse oximetry estimates how saturated hemoglobin is with oxygen, and ABGs provide the arterial oxygen tension and oxygen content, reflecting how effectively oxygen is reaching tissues. The idea highlighted here is the end result: a state of adequate oxygen in the blood to supply tissues.

Ventilation describes moving air in and out of the lungs, which is a prerequisite for oxygenation but does not measure the oxygen content delivered to tissues. Perfusion is the blood flow to tissues, crucial for delivering oxygen but again not the measurement of oxygenation itself. Hematopoiesis is the production of blood cells, not related to the measurement of oxygenation.

Ventilation

Hematopoiesis

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