What occurs during phase three of wound repair?

• A. Hemostasis occurs
• B. Wound dehiscence occurs
• C. Infection risk increases
• D. Granulation tissue forms from fibroblasts and collagen, covered with epithelial tissue

Answer: (D)

Phase three involves the proliferative activity where granulation tissue forms in the wound bed. Fibroblasts lay down collagen and extracellular matrix, creating a vascular, fleshy bed that provides strength and support. This tissue is then covered by migrating epithelial cells to restore the surface. That description fits the choice describing granulation tissue formation from fibroblasts and collagen, covered with epithelial tissue. Hemostasis happens at the moment of injury, not in this phase; dehiscence is a complication rather than a phase event; infection risk is an ongoing concern but not the defining process of this phase.